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400,401,402 In liver diseases like non-alcoholic fatty liver disease (NAFLD) and cirrhosis, mitochondrial dysfunction leads to impaired fatty acid oxidation, excessive ROS production, and oxidative stress
IV doses of 25-400 mcg/kg for safety studies Important: These are experimental doses used in animal studies and cannot be extrapolated to other species due to significant differences in metabolism, pharmacokinetics, receptor expression, peptide degradation rates, and tissue distribution patterns
While occasional moderate consumption probably does not negate treatment benefits entirely, heavy drinking during active healing protocols undermines the process
Future work will focus on refining the docking protocol and conducting in vitro and in vivo experiments to confirm the predicted interactions