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There is also a risk that, because it promotes blood vessel generation, it might also speed the growth of tumors, if the user happens to already have one

Increased risk of seizures (tell your doctor if you have a seizure disorder and avoid taking Contrave with a high-fat meal to lower this risk)

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46 High intratumoral expression of CYP3A4 can accelerate the metabolic inactivation of chemotherapeutic agents such as paclitaxel and docetaxel, thereby reducing local drug bioavailability, diminishing therapeutic efficacy, and ultimately contributing to drug resistance

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