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In patients with DM2 the incretin response is diminished, but the insulinotropic effect of GLP-1 is conserved.28 Under normal conditions GLP-1 has a short half-life (approximately 2 min), as it is rapidly degraded by dipeptidylpeptidase 4, so GLP-1 analogues resistant to this enzyme have been developed for the treatment of DM2.29 arGLP-1: glucagon-like peptide 1 receptor agonist
Compounded GLP-1 from licensed 503A pharmacies uses the same active pharmaceutical ingredients as branded products and meets identical sterility and potency standards
Diabetologia (2017) 60:185161
10.3389/fncel.2020.00219 168 LiJ.VitielloM
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