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observed that long-term administration of green tea catechins to AD model mice significantly ameliorated cognitive impairment, accompanied by reduced ROS levels and enhanced antioxidant capacity in the hippocampus and cortex (133)

The additional potential of THR agonists to improve cardiometabolic outcomes has warranted further investigation through an ongoing phase 2B clinical trial (NCT04173065) for MASH lasting 52 weeks

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However, those experiencing side effects such as nausea, vomiting, or diarrhea should contact a doctor promptly, as dehydration from these effects may temporarily stress kidney function