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+ It is used as an inhibitor of nicotinamide N-methyltransferase, the enzyme that transfers a methyl group from SAM to nicotinamide to form 1-methylnicotinamide and SAH

Clinical trials have highlighted significant weight reduction in participants without diabetes, with many experiencing a decrease in body weight ranging from 10% to 15% from their baseline over 68 weeks when combined with lifestyle modifications like diet and exercise

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