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The peptide's pharmacokinetics in dogs absorption, half-life, and clearance have not been characterized, so neither dosing frequency nor the ideal timing of administration relative to an injury is known
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Interestingly, a recent study provides new insights into this dilemma [90]
These long-term thiomethyl metabolites have great potential in future clinical studies in order to provide a more reliable history of APAP ingestion in case of acute intoxication or to study underlying causes involved in APAP-induced hepatotoxicity
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