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Esposito K, Giugliano F, Maiorino MI, Giugliano D
We simply do not know
Although GIP receptor activation may exert anti-emetic effects through brainstem modulation, these effects appear insufficient to completely counterbalance GLP-1 mediated emesis during early treatment and dose escalation ( In contrast, glucagon receptor activation is independently associated with nausea and vomiting through both central and peripheral mechanisms, including effects on gastric motility and autonomic signaling
BPC-157 is typically administered via subcutaneous injection, and little is known at this time about potential side effects
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