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This study formulated clear causal questions relevant to clinical decision-making by specifying a target trial emulation framework for pairwise comparisons of three common second-line therapies

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Bidirectional Communication Bidirectional communication manifests in multiple experimental paradigms: From brain to gut: Selye-type stress leading to gastroduodenal ulcers was counteracted by BPC-157, which modulated hypothalamic-pituitary-adrenal (HPA) axis function and vagal signaling