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Path 2: Moderate BMI + Serious Health Condition BMI of 30 or higher PLUS one of these: Heart failure (ask your doctor if you have "preserved ejection fraction" type) High blood pressure that's hard to control (still above 140/90 despite 2+ medicines) Chronic kidney disease (stage 3a or higher your doctor can confirm) Path 3: Lower BMI + Heart/Stroke History BMI of 27 or higher PLUS one of these: Pre-diabetes Previous heart attack Previous stroke Peripheral artery disease with symptoms (leg pain when walking) Important timing: These requirements are based on when you FIRST started the GLP-1 medication not your current weight or health
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FDA has also approved dapagliflozin for treatment for CKD (2021) [26] and has given priority review for empagliflozin to potentially treat heart failure not associated with left ventricular ejection fraction [27]
Phase 2 trials will begin later this year
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