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In sharp contrast, someone whose deficiency is purely diet-related might just need a short series of shots to replenish their stores before they can switch to high-dose oral supplements

Do IM injections hurt

In some cases, blood clots have occurred (again, this is typically with a very high dosage, and it is possibly a complication of other medical conditions, or other medications which interact adversely with the B12)

Once a patient is on a maintenance dose, their B12 levels are generally stable, and a single days difference is unlikely to have a clinical impact