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Melatonin administration to wild-type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis

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The short biological half-life is due to a rapid enzymatic degradation of GLP-1 (and GIP also) by the enzyme dipeptidyl peptidase IV (DPP-4) (8)

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According to the degree of severity, stroke-related disability led to premature death with disability-adjusted life-years (DALYs) (47)

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