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This effect is thought to be due to Ritalins action on the central nervous system, which can alter the brains regulation of hunger signals

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Some patients have even experienced serious GI issues first before developing DVT later on

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Semaglutide reduced proteins involved in vascular inflammation and remodeling, including NT-proBNP, angiopoietin-2 (ANGPT2), thrombospondin-2 (THBS2), macrophage scavenger receptor-1 extracellular domain (MSR1), and tenascin-C (TNC), suggesting vascular benefits beyond weight loss and glycemic control