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Indeed, the most frequent pathogenic variants in the SCL12A3 gene are those that result in lack of proper glycosylation of the NCC protein which prevents its trafficking to the membrane or interferes with its ability to transport Na + and Cl

Van Dycke, K

Glutathione and glutathione reductase

Proteomic analysis of protein nitration in aging skeletal muscle and identification of nitrotyrosine-containing sequences in vivo by nanoelectrospray ionization tandem mass spectrometry