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Consider contacting your GP if you experience: Persistent or significant decrease in libido that affects your quality of life or relationships Changes in sexual function accompanied by other concerning symptoms (mood changes, fatigue, pain) Erectile dysfunction or other physical difficulties with sexual activity Relationship difficulties related to changes in intimacy Symptoms suggesting hormonal imbalance (irregular periods, hot flushes, changes in body hair) Seek immediate medical attention if you experience: Severe, persistent abdominal pain, especially if radiating to the back, with or without vomiting (possible pancreatitis) Right upper abdominal pain, jaundice (yellowing of skin/eyes), or fever (possible gallbladder disease) Your healthcare provider can conduct a comprehensive assessment to identify potential contributing factors: Medication review : Evaluating all current medications, as some drugs (antidepressants, blood pressure medications, hormonal contraceptives) are known to affect libido Physical examination : Checking for signs of hormonal imbalance or other medical conditions Blood tests : Assessing hormone levels (testosterone, thyroid function), vitamin deficiencies, or metabolic markers if clinically indicated Mental health evaluation : Screening for depression, anxiety, or stress that may impact sexual function For erectile dysfunction, your GP may assess cardiovascular risk factors and consider referral if symptoms persist or if low testosterone is suspected
Peer support groups, either in person or online, can also provide valuable emotional support from others undergoing similar experiences with weight management medications
Blood Pressure GLP-1 RAs modestly reduce blood pressure, with more potent effects observed in patients with established hypertension
The LEADER trial (cardiovascular outcomes study in type 2 diabetes) showed that liraglutide, a similar GLP-1 agonist, reduced major adverse cardiac events by 13%
Aldn M, Olofsson Falla F, Yang D, et al
