nejm semaglutide heart failure In patients with type 2 diabetes and atherosclerotic cardiovascular disease, tirzepatide was noninferior to dulaglutide with respect to major cardiovascular events. Read the full SURPASS-CVOT trial Semaglutide: The Drug of Today

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This is mechanistically distinct from phosphodiesterase-5 inhibitors like sildenafil, which act peripherally on vascular smooth muscle

The maintenance dose strategy explained Maintenance dosing deserves its own deep dive because it represents the middle ground that works for the largest number of patients

A patient with untreated sleep apnea and there is a meaningful prevalence of undiagnosed sleep apnea in middle Georgia, particularly among the men I see from Fort Benning who deploy on shifted schedules for years will plateau on any weight loss intervention until the sleep problem is addressed

I was not able to sleep, then exhausted all day, Nirchi tells SELF