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It probably does not hurt (at the doses used in compounded formulations)
Reviewing the available literature - no adverse hepatic, or renal effects have been published.If Glutathione is administered too rapidly it can cause brief shortness of breath and a slight head pressure sensation
G.KendirciM.MaternR.CockerhamY.MyersL.SikkaS
Also, it has been shown that a folate precursor synthesis gene, ADCS, is expressed in root tips (Nziengui et al., 2018)
The natural sources are all animal-derived: meat, fish, eggs, milk and cheese
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