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The C=O oxygen is converted into a good leaving group and eliminated in a later step: Amide Dehydration Mechanism by P 2 O 5 2 O 5 P 2 O 5 is another powerful dehydration agent, which converts amides to nitriles by a similar mechanism: Need some good practice on the reactions of carboxylic acids and their derivatives
van Ophoven, A., Pokupic, S., Heinecke, A
For semaglutide dosing, the best syringe depends on your dose and concentration
Yes, but only slightly and inconsistently
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