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Potential risks include infection, scarring, changes in nipple sensation, difficulty breastfeeding, asymmetry, and in rare cases, partial or total loss of the nipple or areola
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(7) These are observational cohorts with their own populations, confounders, and limits, so the numbers describe an association in a group, not a prediction for an individual
Self-reported community sources commonly describe rotating sites (abdomen, near the injury site for community-described "site-directed" use) and warming the vial to room temperature as factors that reduce reaction frequency
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