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RSV infection affects cellular mitochondrial membrane potential by enhancing mtROS generation, which facilitates viral infection 34
PDGF induces the activation of extracellular signal-regulated kinase and Akt/mTOR pathways, which are serine/threonine protein kinases that are critical in cell growth, differentiation, proliferation, migration, and survival
Microscopically, MMNST features spindle-shaped and epithelioid cells in intertwining fascicles, with a significant concentration of melanin both in the neoplastic cells and in the associated melanophages ( Clinical presentation depends on anatomical location
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