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Earlier studies suggest that semaglutide (sold as Ozempic, Wegovy, and Rybelsus) may cause more digestive issues, including diarrhea, than older GLP-1 medications like liraglutide (Saxenda and Victoza)
All products are sold strictly for research purposes only
In a 3-month randomized controlled study of type 2 diabetes, it was found that the combination of liraglutide and sitagliptin had no effect on the composition of intestinal flora, had no effect on the alpha and beta diversity, but liraglutide resulted in an elevation of deoxycholic acid (DCA) levels, indicating potential modulation of bile acid metabolism (Smits et al., 2021)
As shown in Table 1, no significant difference in sex ratio or age was observed between controls and patients ( p = 0.807 and p = 0.251, respectively)
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