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The single-cell sequencing results similarly demonstrated that high glutathione metabolism levels are associated with CD8+ T cell exhaustion

Then, we further examined the protein level of UGT2B1 and found that the expression of UGT2B1 protein was decreased in rat liver tissue of tamoxifen group (Fig

the mixture should be refrigerated if not used immediately

Moreover, immune function analysis revealed that elevated glutathione metabolism correlated with a decline in multiple immune functions, including antigen presentation, T cell activation, effector immune responses, and cytokine signaling