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These fibers reach the colon where they are fermented by gut bacteria into butyrate

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Purification of naringin and neohesperidin from Huyou (Citrus changshanensis) fruit and their effects on glucose consumption in human HepG2 cells

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Common animal models include inflammatory bowel disease (IBD) model, ischemia-reperfusion (I/R) injury model, radiation-induced intestinal injury model, etc

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This means the drug mimics the bodys hormone that stimulates production of the pigment melanin

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doi: 10.1038/ncomms13572 28 BrohanJGoudraBG

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