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Description

Rodent toxicity studies from the Sikiric group have not identified significant acute toxicity

6A, Supplementary Fig

Journal of Experimental Orthopaedics, 2016

While these existing tags have enjoyed an extremely wide adoption, they carry specific drawbacks: the very short tags represent peptides that can adopt disordered structures and thus trigger misfolding of the protein under study, while the full-length protein tags add a burden to the cellular machinery when the sometimes too-large fusion protein needs to be produced