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LPS stimulation significantly induced the phosphorylation of NF-B p65 at Ser536 and promoted its nuclear translocation

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Neutrophilia causes excessive ROS production that aggravates the host immunopathological response, leading to a more severe disease (Laforge et al., 2020)

The optimal cutoff of GSH 1.895 mM achieved 86.5% sensitivity and 73.7% specificity, comparing favorably with other proposed migraine markers and with recently reported AUC values for thalamic GABA in differentiating chronic migraine from controls (AUC = 0.83) [11]

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