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External resources for researchers PubChem 5-Amino-1-methylquinolinium Open-access paper selective small-molecule NNMT inhibitors PubMed NNMT inhibition in preclinical metabolic research Related research products Disclaimer Used solely for in vitro experiments and cannot be: Used in clinical trials involving humans Administered to humans as part of an experiment or investigation Supplied to another party for human investigational use

NAD+ & cellular metabolism Explored in cell research on how NNMT inhibition affects NAD+ and SAM levels investigational, animal and in-vitro only

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The peptide contains an internal disulfide bond between the two cysteine residues, which is critical for its three-dimensional conformation

That enzyme is NNMT, nicotinamide N-methyltransferase