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What is fascinating is that their effects are not limited to alcohol: preclinical and correlational data indicate possible benefits in decreasing use of nicotine and opioids, which makes sense as alcohol, cannabis, opioid, and nicotine use disorders cluster together genetically into one brain disorder

"Yes, that's why our abstract title asks, 'Too much of a good thing?' When I'm talking to patients about going on these drugs, they're like, 'I don't want to go on another medicine.' I say, 'You know what

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373 Next-generation HSP90 inhibitors aim to overcome these limitations