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Summary Half a century has passed since the discovery of GLP-1, which has provided a new way for humans to fight diabetes

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With ongoing research, new formulations, and combination therapies on the horizon, patients can expect even more innovative options for managing their diabetes

Conversely, some studies report decreased depression risk with GLP-1RA use and suggest potential antidepressant effects

A RCT of liraglutide reported numerically more pancreatic cancer cases in the liraglutide group than those reported in the placebo group (13/4,668 vs