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Presented for research literature review only McGuire DK et al

[1] Investigational status: large-scale human trials still needed

J Am Coll Cardiol 2024;83:1386-98.ArticlePubMed 35

This phenomenon may also be influenced by its regulation of GSH metabolism

Further, on evaluating hepatic antioxidant capacity, it was significantly attenuated in MTX group in comparison with CTRL as demonstrated by the significantly lower hepatic GSH and SOD activity (Figures 3B, C)