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Symptoms of B12 deficiency may include Megaloblastic anemia (large red blood cells with abnormal nuclei) Fatigue Paleness Heart palpitations Dementia Weight loss Infertility Numbness and tingling in hands and feet Depression, mania, delirium, psychosis Poor pregnancy and breastfeeding outcomes (neural tube defects, developmental delays, failure to thrive, anemia in offspring) Low red and white blood cell counts or platelets Glossitis of the tongue Erectile dysfunction or bowel/urinary incontinence Recommended Daily Intake for B12 Recommended Dietary Allowance (RDA) Daily B12 requirements depend on age, sex, and dietary intake (5) Assessing B12 Status Typically serum B12 levels are used to determine vitamin B12 deficiency (keep in mind normal value ranges may vary slightly depending on the laboratory)

Working in a clean environment, using sterile supplies, and preparing your workspace before opening any vial are some of the simplest ways to improve laboratory consistency and reduce contamination risk

Go very slowly and gently pull back on the needle plunger until you get the appropriate units for the dosage

Dietary deficiency of Vitamin B12 can result from poor diets or among strict vegetarians who choose not to consume any animal products

You add bacteriostatic water to dissolve it into a liquid form