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GHK-Cu offers a complementary neurotrophic gene-expression angle (BDNF/NGF upregulation, A-copper interaction biology) that is mechanistically distinct and particularly relevant to neurodegeneration research
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We found that HDL cholesterol and LDL cholesterol levels were higher and HbA1c levels lower in ALT responders than in non-responders
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Other groups have reported increased efficacy with 5FU and metformin in models of acquired resistance 53,54,55,56 , in spheroid culture 53 or xenograft/PDX models 57,58,59 , but the potential of combined 5FUCI inhibitor co-treatment in a chemo-naive, immune-competent setting requires further investigation
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