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Research vials commonly cost about $49 to $100 in 2026, far less than wellness clinics

Transfusion (2021)

Ongoing Support Manage refills and reach your care team anytime through your secure patient portal

Major Weight Loss Results In a Phase 2 clinical trial with 338 adults, participants on the highest dose lost an average of 24.2% of their body weight in 48 weeks

When activated, MC1R triggers a signaling cascade: MC1R activation cAMP increase cAMP activates MITF (master melanocyte transcription factor) MITF upregulates tyrosinase and related enzymes Pheomelanin production shifts to eumelanin production This last point is the key insight