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The dysesthesia safety signal and the novel triple-agonist mechanism might prompt the FDA to seek external input

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It has been reported that the CPT1C isoform is overexpressed in human tumor cells such as neuroblastoma, several sarcomas of soft-tissues and lung, and malignant peripheral nerve sheath tumors (associated with neurofibromatosis type 1) 45

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Appetite decreases, and portions shrink, so its easy for nutrients to be left behind