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Care 21, 90
doi: 10.1097/HJH.0000000000001767 114
Chemical irritation occurs when glutathione solution pH (typically 6.57.5 for injectable formulations) differs significantly from tissue pH (7.357.45)
Coordination state and stoichiometry matter for reproducibility, which is why generic GHK-Cu labeling without lot-matched characterization is a weak signal
[1] Complexation prevents the metal ions from reacting with molecules in the body, and enable them to be dissolved in blood and eliminated in urine
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