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Red flags warranting slower discontinuation: rapid hunger return despite dose reduction, loss of satiety cues within 12 weeks, mood changes, or blood glucose elevation
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You may notice mild redness at the injection site for a few hours
Additionally, individuals with demanding physical or cognitive jobs, athletes, or those with psychiatric conditions affecting energy perception should discuss fatigue risk explicitly with their provider before treatment begins
Interestingly, however, retatrutide has the same efficacy as semaglutide at a dose that is more than 30 times smaller[3]
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