paraxanthine increases catalase glutathione Catalase, Peroxidase, and Peroxiredoxin 2 in Erythrocyte Cytosol and Membrane in Hereditary Spherocytosis, Sickle Cell Disease, and β-Thalassemia 1-Methylxanthine enhances memory and neurotransmitter

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(Source 1) While this study was small, it's highly encouraging and validates what functional medicine doctors see in practice

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Moreover, as shown in the present study, the GSH levels do not necessarily decrease in parallel with ROS production because of its compensatory mechanism