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For example, better outcomes can be achieved with a combination of the DPP-4 inhibitor and metformin or TZD pioglitazone, and insulin and metformin, glyburide, and pioglitazone (Cersosimo et al., 2018)

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Considering the documented changes in sensitization and upregulation of TRPV1 in the complete Freunds adjuvant (CFA)-induced inflammatory pain model, CFA was utilized to induce chronic inflammatory pain in mice 43

[Glutathione depletion during pregnancy studies - see full reference list] Thornton SL, Minns AB