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In this line, a recent phase I/II trial in early stage AD showed that repeatedly opening the BBB with ultrasound is well-tolerated and may be associated with a reduction of amyloid burden (Epelbaum et al., 2022)
Retrieved from Gadde, K
Categorization of patients The CKD status of patients at baseline was determined according to KDIGO guidelines, where a combined variable consisting of eGFR [six categories ranging from normal/high eGFR (G1, 90 mL/min/1.73 m 2 ) to kidney failure (G5, 300 mg/g)] is considered ( Supplementary Table 1 ) ( Collected variables The following data were collected at baseline, and at the 6- and 12-month follow-up visits: anthropometric parameters, namely, weight, body mass index (BMI), waist circumference, and blood pressure
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