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Older patients or those with multiple comorbidities may experience slower improvement

It is associated with increased risk for several serious health problems, including: hypertension cardiovascular disease type 2 diabetes cancer gout cognitive dysfunction autoimmune disorders pregnancy complications Fortunately, effective treatment options are available for sleep apnea, and dietary and lifestyle changes can reduce the severity of disease

Additionally, metformin has been shown to improve sputum culture conversion and lower the relapse rate of patients with TB-DM [122]