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Missing one or two days in a cycle will not significantly affect outcomes
Findings from the rica registry
If these ROS overwhelm the cellular antioxidant response, cell death and tissue necrosis occurs, resulting in severe hepatotoxicity that can lead to death 6
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Similar to RNK06138, RNK06395 showed specific accumulation and prolonged pharmacokinetics in tumors compared to those in normal tissues in the MOLP-8 xenograft model, as well as higher drug concentrations in tumors than in tissues 7 days after administration (Fig
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