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People taking semaglutide for weight loss may experience: Dizziness Fatigue Gastrointestinal issues, such as diarrhea, constipation and gassiness Headache Stomach issues, including nausea, vomiting, pain or distension (bloat) Gastrointestinal issues are the most common complaint among people just starting semaglutide

Christine Sofie Fuchs Jacobsen3

The side effect profile remains comparable between genders, though women reported slightly higher nausea rates at 31% compared to 24% for men

Tirzepatide: FDA 2022, EMA 2022

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