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114,165 The main causes of autophagy inhibition by mTOR are Ser757 phosphorylation and ULK1 suppression, which perturb the interaction between ULK1 and AMPK
The WHO has also released its first guideline for treating obesity as a chronic, relapsing disease in which there is a conditional recommendation stating that GLP-1 RAs may be used for long-term treatment for obesity [45]
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