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These findings suggest that it is possible to increase GLP-1 secretion and manage T2DM and its complications by restoring and improving the gut microbiota [158]
How It Works Tirzepatide attaches to two receptors (GLP-1 and GIP), unlike previous GLP-1 analogs which only attach to one, resulting in increased overall weight loss (around 20%)
In one nationwide study, teens maintained a 20% decrease in BMI a decade after surgery
As always, careful consideration of dosage, safety, and legal compliance is essential when exploring these compounds
If side effects from semaglutide are persistent and difficult to manage, discussing a switch to tirzepatide with a provider might be an option, as the body might react differently to the other active ingredient
