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It is converted to coenzyme B12 in the body and in this form facilitates the conversion of homocysteine to methionine (methylcobalamin) and plays an important role in converting methylmalonyl-coenzyme A to succinyl-Co-A (fatty acid and amino acid metabolism)
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Adenine nucleotide translocase (ANT) is activated, mitochondrial transport of ATP and ADP restores energy supply
Cells were passaged when they reached 7080% confluence, again maintaining 30 10 6 cells at each serial passage, with 5FU added in fresh media every 3 days
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