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In a combined fertility and embryo-fetal development study in rats, subcutaneous doses of 0.01, 0.03 and 0.09 mg/kg/day (0.1-, 0.4-, and 1.1-fold the MRHD) were administered to male and female rats
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These preliminary results open fascinating research avenues, although they are still far from clinical application
Moreover, reducing the senescent testosterone-producing cell burden may leave a higher proportion of cells that still express the enzymes needed to make testosterone, or may allow remaining testosterone-producing cells to restore some of that enzyme expression
10.1038/s41598-018-26296-6 86 RibasV.Garca-RuizC.Fernndez-ChecaJ
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