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In this study, we investigated the effects of dysregulated glutathione homeostasis, a principal feature of oxidative stress, on TNF-induced hepatotoxicity and its mechanistic implications in NAFLD progression

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For metformin and warfarin, the 90% CIs for ratios were evaluated against the pre-specified interval in the same way as for the primary endpoints

Biomarker assessment of glutathione and related markers like cysteine, glycine, and glutamate can reveal whether supplementation directly addresses a documented deficiency or addresses downstream metabolic stress

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