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TB-500 is dosed less frequently, typically once or twice per week during a loading phase and once every two weeks during maintenance, reflecting its longer half-life and systemic distribution pattern

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DOI: 10.1016/S0140-6736(23)01163-7

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Suitability is determined only after an individualized clinical review of the patients developmental profile, medical history, associated comorbidities, medication use, and available diagnostic workup