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In obesity, NNMT activity is unusually high in fat cells, which means a lot of nicotinamide gets thrown out before it can be turned into NAD+
However, deficiency is common, especially in people with low stomach acid, digestive conditions, vegan or vegetarian diets, or age-related absorption decline
It is not a peptide
These studies only show a link between vitamin B12 deficiencies and weight gain, Matthew Cowling, D.O., a physical medicine and rehabilitation specialist in Madison, Wisconsin who specializes in weight loss, previously told The Edge
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