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B12 is water-soluble, and excess amounts are typically excreted by the body
B12 shots are affordable enough that we advise to stay well within the expiration date, and avoiding expired B12 shots whenever possible
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336 In 60 patients with treatment-resistant depression, adding 25 mg zinc daily to treatment with the tricyclic antidepressant imipramine (Tofranil) for 12 weeks led to a more rapid and robust treatment response compared with placebo
Instead, they are made in pharmacies when there is a medical reason, sometimes to help with possible B12 deficiencies that might happen during use
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