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But reduced calorie intake also means reduced nutrient intake
By mimicking the gut hormone GLP1, it enhances insulin release, suppresses glucagon, and delays stomach emptyingso your brain registers fullness sooner and you physically eat less
Across outcomes, agent-level estimates for tirzepatide compared with placebo were predominantly low to very low certainty, driven by indirect-only evidence and imprecision
Ratnayake, D
These are pragmatic upper bounds, not formal equivalence doses
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