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Its detoxification capabilities are critical for liver function, where glutathione facilitates conjugation reactions that render toxins more water-soluble for elimination

In vivo , knockdown of LPCAT3 aggravates OA progression and inflammation, while pharmacological inhibition of ACSL4 partially rescues these effects (76)

Ding Q, Luo Y, Wu H, Tao J, Zhang Y, Yin G, et al

Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models